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. 2022 Mar 3;2022(3):CD014328. doi: 10.1002/14651858.CD014328

1. Characteristics of participants.

Study ID Age range (years) Osteoarthritis and criteria Meniscal tear and criteria
Trials with a placebo control
Moseley 1996 < 70 ACR‐defined or clinically diagnosed No criteria re presence/absence specified
Moseley 2002 < 70 ACR‐defined or clinically diagnosed No criteria re presence/absence specified
Sihvonen 2013 35 to 65 KL grade 0 to 1 Medial meniscal tear on MRI
Roos 2018 35 to 55 KL grade 0 to 2 Medial meniscal tear on MRI
Trials with an exercise control
Gauffin 2014 45 to 64 < 50% joint narrowing Clinically suspected meniscal injury (66/75 randomised to surgery received surgery but only 56 had partial meniscectomies (1 loose bodies removed, 1 synovectomy, 1 partial resection ACL remnant, 8 deemed surgery unnecessary; of the 16/75 who crossed over to surgery, 11 had 11 partial meniscectomies (1 loose bodies removed, 1 microfracture, 1 partial resection ACL remnant, 1 deemed surgery unnecessary and 2 unknown). 3 ACL total ruptures were found (2 surgical group, 1 in non‐surgery group who crossed over toe surgery)
Herrlin 2007 45 to 65 Grade 0 to 1 Ahlbacks classification Medial meniscal tear
Katz 2013 45 or older meniscal tear, mild to mod OA, KL grade 0‐3 KL grade 0 to 3 Meniscal tear
Kirkley 2008 18 or older KL grade 2 to 4 except grade 4 if involves both compartments Exclude large meniscal tear (bucket handle tear) mainly clinical, few had MRIs
Kise 2016 35 to 60 KL grade 0 to 2 Medial meniscal tear
Osteras 2012 35 to 60 KL grade 0 to 2 Meniscal tear
Van de Graaf 2018 45 to 70 KL grade 0 to 3 Meniscal tear
Yim 2013 no age restriction specified KL grade 0 to 1 Medial posterior horn horizontal meniscal tear on MRI
Trials with other controls
Saeed 2015 >40 KL grade 2 and 3 No criteria re presence/absence specified
Vermesan 2013 Not specified medial compartment cartilage and meniscus lesions on MRI Medial compartment cartilage and meniscus lesions on MRI
Chang 1993 >20 KL grades 1 to 3 No criteria re presence/absence specified
Merchan 1993 Not specified minimal joint space narrowing and formation of small osteophytes No criteria re presence/absence specified

ACR: American College of Rheumatology; ACL: anterior cruciate ligament; KL grade: Kellgren‐Lawrence classification grade; MRI: magnetic resonance imaging