Table II.
Pregnancy and maternal outcomes after onset of systemic sclerosis
| Author | Years | Design | No. of SSc patients | No. of pregnancies/deliveries | Renal crisis rate | Hypertension rate | Pre-eclampsia rate | PROM rate | Cesarean delivery rate |
|---|---|---|---|---|---|---|---|---|---|
| Steen and Medsger (7) | 1972–1986 | Retrospective/questionnaire | NA | 89/74 | 2% | ||||
| Steen (15) | 1987–1996 | Prospective | 59 | 91/67 | 2% | ||||
| Sampaio-Barros et al. (2) | 1991–1998 | Retrospective | NA | 42/34 | |||||
| Chakravarty (17) | 2002–2004 | Retrospective cohort study | NA | NA/149 | 23% | 1% | |||
| IMPRESS Study (16) | 2000–2011 | Prospective | 99 | 109/98 | 0% | 2% | 0% | 6% | 52% |
| Chen (18) | 2001–2011 | Retrospective cohort study | 42 | NA/53 | 8% | 64% |
No. = number; PROM = premature rupture of membranes; SSc = systemic sclerosis.
The italicized values represent statistically significant differences.