TABLE 6.

Distribution of B. burgdorferi sensu lato species in 472 isolates cultured from LB patients with different clinical syndromes^a

Specimen	Total no.	B. burgdorferi sensu stricto	B. garinii	B. afzelii	Otherf
		No. (%)	No. (%)	No. (%)	No. (%)
Skin, EMb	308	96 (31.2)	50 (16.2)	156 (50.7)	6 (1.9)
CSFc	68	9 (13.2)	46 (67.7)	10 (14.7)	3 (4.4)
Skin, ACAd	74	3 (3.0)	5 (6.8)	66 (89.2)	0 (0)
Otherse	22	16 (72.8)	3 (13.6)	2 (9.1)	1 (4.5)
Total	472	124 (26.3)	104 (22.0)	234 (49.6)	10 (2.1)

^aOnly isolates with indication of clinical source and belonging to Borrelia species in published papers were included for analysis. These isolates were recovered from patients from 18 countries including Germany (n = 123), United States (n = 92), The Netherlands (n = 74), Slovenia (n = 63), Austria (n = 45), Denmark (n = 21), Japan (n = 12), Sweden (n = 10), Russia (n = 7), Switzerland (n = 6), Czech Republic (n = 6), China (n = 4), France (n = 3), Italy (n = 2), Poland (n = 1), Croatia (n = 1), Lithuania (n = 1), and Australia (n = 1). Isolates with mixed infections of two species were excluded. A detailed list of Borrelia isolates included in our analysis is available upon request. 

^bIsolates are from references 1, 20, 34, 64, 70, 85, 132, 137, 155, 168, 194, 197, 200, 251, 259, 268, 273, 281, and 285. 

^cIsolates are from references 1, 14, 33, 85, 132, 137, 141, 251, and 259. 

^dIsolates are from references 20, 85, 132, 137, 194, 229, 259, 268, and 273. 

^eThis includes 17 isolates from human blood, 3 from synovial fluid, 1 from myocardial samples, and 1 from the skin of a patient with lymphocytoma (12, 216, 234). 

^fThis includes 9 Slovenian isolates genetically similar to North America isolate 25015, which belonged to B. bissettii (201), and 1 isolate from a patient with EM in The Netherlands (265).