Table 1.

Kinetic Parameters of CL11, CL11-M, and CL11-E Binding to 58rRNA Determined by SPR.

Protein	k on (1/M×s)	k off (1/s)	K D (M) (Koff/Kon)
CL11	1.2 ± 0.4×104	3.0 ± 0.2×10−4	2.5 ± 0.6×10−8
CL11-M	1.9 ± 0.9×104	4.5 ± 0.9×10−4	2.4 ± 0.9×10−8
CL11-E	1.6 ± 0.8×103	3.6 ± 0.8×10−6	2.2 ± 0.3×10−9

The SD (±) was calculated from two different sets of experiments each with three different protein concentrations.