Table 3.
Comparison of RPQ Scores by Group and Time
| Comparison | Raw mean diff. | Modeled estimates |
|||||
|---|---|---|---|---|---|---|---|
| Linear |
Ranked |
||||||
| B | 95% CI | p | p MC | p | p MC | ||
| TBI vs. OTC at 2wk | 10.68 | 10.75 | (8.98, 12.51) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. OTC at 3mo | 8.43 | 8.54 | (6.74, 10.34) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. OTC at 6mo | 7.67 | 7.93 | (6.09, 9.78) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. OTC at 1yr | 6.89 | 6.59 | (4.72, 8.45) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. FC at 2wk | 14.58 | 14.95 | (13.33, 16.58) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. FC at 3mo | 10.88 | 10.76 | (9.11, 12.41) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. FC at 6mo | 8.32 | 8.29 | (6.64, 9.95) | <0.001 | <0.001 | <0.001 | <0.001 |
| TBI vs. FC at 1yr | 7.50 | 7.48 | (5.80, 9.16) | <0.001 | <0.001 | <0.001 | <0.001 |
| OTC vs. FC at 2wk | 3.90 | 4.21 | (1.96, 6.45) | <0.001 | <0.001 | <0.001 | <0.001 |
| OTC vs. FC at 3mo | 2.45 | 2.23 | (−0.07, 4.52) | 0.057 | 0.081 | 0.003 | 0.004 |
| OTC vs. FC at 6mo | 0.65 | 0.36 | (−1.96, 2.68) | 0.761 | 0.804 | 0.609 | 0.652 |
| OTC vs. FC at 1yr | 0.61 | 0.89 | (−1.46, 3.25) | 0.457 | 0.549 | 0.747 | 0.772 |
| 3mo vs. 2wk for TBI | –4.28 | –4.59 | (−5.10, −4.08) | <0.001 | <0.001 | <0.001 | <0.001 |
| 6mo vs. 2wk for TBI | –5.38 | –5.71 | (−6.23, −5.19) | <0.001 | <0.001 | <0.001 | <0.001 |
| 1yr vs. 2wk for TBI | –5.94 | –6.35 | (−6.89, −5.82) | <0.001 | <0.001 | <0.001 | <0.001 |
| 6mo vs. 3mo for TBI | –1.10 | –1.12 | (−1.64, −0.60) | <0.001 | <0.001 | <0.001 | <0.001 |
| 1yr vs. 3mo for TBI | –1.66 | –1.76 | (−2.29, −1.23) | <0.001 | <0.001 | <0.001 | <0.001 |
| 1yr vs. 6mo for TBI | –0.56 | –0.64 | (−1.18, −0.11) | 0.018 | 0.030 | 0.023 | 0.031 |
| 3mo vs. 2wk for OTC | –2.02 | –2.38 | (−3.79, −0.98) | 0.001 | 0.002 | <0.001 | <0.001 |
| 6mo vs. 2wk for OTC | –2.37 | –2.90 | (−4.34, −1.45) | <0.001 | <0.001 | <0.001 | <0.001 |
| 1yr vs. 2wk for OTC | –2.15 | –2.19 | (−3.67, −0.72) | 0.004 | 0.006 | <0.001 | <0.001 |
| 6mo vs. 3mo for OTC | –0.35 | –0.51 | (−1.98, 0.95) | 0.491 | 0.566 | 0.139 | 0.174 |
| 1yr vs. 3mo for OTC | –0.13 | 0.19 | (−1.30, 1.68) | 0.804 | 0.804 | 0.233 | 0.279 |
| 1yr vs. 6mo for OTC | 0.22 | 0.70 | (−0.81, 2.22) | 0.362 | 0.452 | 0.800 | 0.800 |
| 3mo vs. 2wk for FC | –0.57 | –0.40 | (−1.63, 0.83) | 0.524 | 0.582 | 0.548 | 0.609 |
| 6mo vs. 2wk for FC | 0.88 | 0.95 | (−0.27, 2.18) | 0.128 | 0.166 | 0.034 | 0.045 |
| 1yr vs. 2wk for FC | 1.13 | 1.12 | (−0.14, 2.38) | 0.081 | 0.110 | 0.007 | 0.011 |
| 6mo vs. 3mo for FC | 1.45 | 1.35 | (0.10, 2.61) | 0.035 | 0.053 | 0.008 | 0.011 |
| 1yr vs. 3mo for FC | 1.71 | 1.52 | (0.23, 2.81) | 0.021 | 0.033 | 0.001 | 0.002 |
| 1yr vs. 6mo for FC | 0.26 | 0.17 | (−1.11, 1.45) | 0.794 | 0.804 | 0.535 | 0.609 |
pMC = p value adjusted for multiple comparisons (m = 30) using a false discovery rate.
RPQ, Rivermead Post-Concussion Symptoms Questionnaire; CI, confidence interval; TBI, traumatic brain injury group; OTC, orthopedic trauma control group; FC, friend control group.