Table 5.

Comparison of RPQ Scores by TBI Severity Subgroup and Time

Comparison	Raw mean diff.	Modeled estimates
		Linear				Ranked
		B	95% CI	p	p MC	p	p MC
mTBI vs. msTBI at 2wk	0.03	–1.35	(−3.55, 0.86)	0.232	0.286	0.022	0.032
mTBI vs. msTBI at 3mo	0.59	0.08	(−1.89, 2.05)	0.935	0.976	0.431	0.493
mTBI vs. msTBI at 6mo	–0.07	0.32	(−1.66, 2.31)	0.750	0.857	0.519	0.553
mTBI vs. msTBI at 1yr	–2.20	–1.89	(−3.89, 0.11)	0.065	0.103	0.004	0.006
3mo vs. 2wk for mTBI	–4.24	–4.48	(−5.06, −3.91)	<0.001	<0.001	<0.001	<0.001
6mo vs. 2wk for mTBI	–5.48	–5.63	(−6.21, −5.04)	<0.001	<0.001	<0.001	<0.001
1yr vs. 2wk for mTBI	–6.25	–6.48	(−7.08, −5.88)	<0.001	<0.001	<0.001	<0.001
6mo vs. 3mo for mTBI	–1.24	–1.14	(−1.74, −0.55)	<0.001	<0.001	<0.001	<0.001
1yr vs. 3mo for mTBI	–2.02	–2.00	(−2.60, −1.39)	<0.001	<0.001	<0.001	<0.001
1yr vs. 6mo for mTBI	–0.77	–0.85	(−1.47, −0.24)	0.006	0.011	0.006	0.009
3mo vs. 2wk for msTBI	–4.79	–5.91	(−7.80, −4.02)	<0.001	<0.001	<0.001	<0.001
6mo vs. 2wk for msTBI	–5.38	–7.29	(−9.22, −5.37)	<0.001	<0.001	<0.001	<0.001
1yr vs. 2wk for msTBI	–4.02	–5.94	(−7.90, −3.97)	<0.001	<0.001	<0.001	<0.001
6mo vs. 3mo for msTBI	–0.59	–1.38	(−2.98, 0.22)	0.090	0.131	0.073	0.098
1yr vs. 3mo for msTBI	0.77	–0.03	(−1.68, 1.63)	0.976	0.976	0.972	0.972
1yr vs. 6mo for msTBI	1.36	1.36	(−0.27, 2.99)	0.103	0.137	0.085	0.104

Statistical significance by mixed-effects linear/rank regression.

p_MC = p value adjusted for multiple comparisons (m = 16) using a false discovery rate.

RPQ, Rivermead Post-Concussion Symptoms Questionnaire; TBI, traumatic brain injury; mTBI, mild TBI; msTBI, moderate or severe TBI.