Figure 1.

Factors influencing morbidity and mortality of the childhood cancer survivor. Each arrow demonstrates a different factor affecting morbidity and mortality which exert their effect along a continuum of care. Note that all effectors can begin exerting influence on morbidity during the period of cancer-directed therapy. Factors are separated into those that cannot be modified (red), those for which future interventions are plausible (yellow) and those for which there are known targets for interventions or areas where therapy and surveillance have already been modified (blue).