Table 2.
Independent Predictors of In-Hospital Deaths from Multivariable Logistic-Regression Analysis in Patients Hospitalized with COVID-19
Sub-Sample with Biomarkers (n = 858)a | ||||
---|---|---|---|---|
Variable | OR | L95% CI | U95% CI | P-value |
Age (years)b | 0.02 | |||
18 to 49 | (ref) | - | - | - |
50 to 64 | 1.05 | 0.31 | 3.6 | 0.93 |
65 and older | 2.4 | 0.79 | 7.32 | 0.12 |
Congestive heart failure | 2.88 | 1.73 | 4.79 | <0.001 |
CKD | 3.06 | 1.78 | 5.23 | <0.001 |
ARF | 2.73 | 1.51 | 4.92 | 0.001 |
Dementia | 1.98 | 1.04 | 3.78 | 0.04 |
Cancer | 2.73 | 1.12 | 6.64 | 0.047 |
Thrombocytopenia | 1.75 | 1.01 | 3.05 | 0.047 |
LDH ≥ 280 U/L | 3.28 | 1.93 | 5.58 | <0.001 |
Intercept | 0.004 | 0.001 | 0.02 | <0.001 |
Full Sample without Biomarkers (n = 1626)c | ||||
Variable | OR | L95% CI | U95% CI | P-value |
Age (years) | <0.001 | |||
18 to 49 | (ref) | - | - | - |
50 to 64 | 1.69 | 0.61 | 4.66 | 0.31 |
65 and older | 4.46 | 1.75 | 11.36 | 0.002 |
Congestive heart failure | 2.47 | 1.69 | 3.61 | <0.001 |
CKD | 2.19 | 1.51 | 3.19 | <0.001 |
Cancer | 2.3 | 1.13 | 4.69 | 0.02 |
ARF | 3.74 | 2.49 | 5.61 | <0.001 |
ICU | 1.98 | 1.31 | 3 | 0.001 |
Length of stay (days) | 0.02 | |||
<5 | (ref) | - | - | - |
5 to <10 | 0.56 | 0.34 | 0.91 | 0.02 |
10 to <20 | 0.96 | 0.58 | 1.58 | 0.87 |
20 and more | 1.2 | 0.68 | 2.14 | 0.53 |
Intercept | 0.01 | 0.003 | 0.02 | <0.001 |
Notes: aRandom intercept variance estimate and 95% CI for facility: 0.25 (0.02, 2.75). Random intercept variance estimate and 95% CI for month: 0.03 (0.0002, 5.28). bFurther combined for statistical analysis purposes. cRandom intercept variance estimate and 95% CI for facility: 0.08 (0.01, 0.72). Random intercept variance estimate and 95% CI for month: 0.12 (0.02, 0.56).
Abbreviations: CKD, chronic kidney disease; ARF, acute respiratory failure; LDH, lactate dehydrogenase; ICU, intensive care unit.