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. 2022 Feb 27;15:2207–2214. doi: 10.2147/IJGM.S355083

Table 2.

Independent Predictors of In-Hospital Deaths from Multivariable Logistic-Regression Analysis in Patients Hospitalized with COVID-19

Sub-Sample with Biomarkers (n = 858)a
Variable OR L95% CI U95% CI P-value
Age (years)b 0.02
18 to 49 (ref) - - -
50 to 64 1.05 0.31 3.6 0.93
65 and older 2.4 0.79 7.32 0.12
Congestive heart failure 2.88 1.73 4.79 <0.001
CKD 3.06 1.78 5.23 <0.001
ARF 2.73 1.51 4.92 0.001
Dementia 1.98 1.04 3.78 0.04
Cancer 2.73 1.12 6.64 0.047
Thrombocytopenia 1.75 1.01 3.05 0.047
LDH ≥ 280 U/L 3.28 1.93 5.58 <0.001
Intercept 0.004 0.001 0.02 <0.001
Full Sample without Biomarkers (n = 1626)c
Variable OR L95% CI U95% CI P-value
Age (years) <0.001
18 to 49 (ref) - - -
50 to 64 1.69 0.61 4.66 0.31
65 and older 4.46 1.75 11.36 0.002
Congestive heart failure 2.47 1.69 3.61 <0.001
CKD 2.19 1.51 3.19 <0.001
Cancer 2.3 1.13 4.69 0.02
ARF 3.74 2.49 5.61 <0.001
ICU 1.98 1.31 3 0.001
Length of stay (days) 0.02
<5 (ref) - - -
5 to <10 0.56 0.34 0.91 0.02
10 to <20 0.96 0.58 1.58 0.87
20 and more 1.2 0.68 2.14 0.53
Intercept 0.01 0.003 0.02 <0.001

Notes: aRandom intercept variance estimate and 95% CI for facility: 0.25 (0.02, 2.75). Random intercept variance estimate and 95% CI for month: 0.03 (0.0002, 5.28). bFurther combined for statistical analysis purposes. cRandom intercept variance estimate and 95% CI for facility: 0.08 (0.01, 0.72). Random intercept variance estimate and 95% CI for month: 0.12 (0.02, 0.56).

Abbreviations: CKD, chronic kidney disease; ARF, acute respiratory failure; LDH, lactate dehydrogenase; ICU, intensive care unit.