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. 2022 Feb 17;9:814610. doi: 10.3389/fcvm.2022.814610

Table 1.

Self-reported demographics, clinical, and Life's Simple 7 data for participants age <50 yrs.

Age <50 years No CVD (n = 696) Age <50 yrs CVD (n = 349) P-value
Age (yrs) 35.3 ± 8.4 39.8 ± 6.7 <0.01
Gender (no., % female) 572 (82.2) 293 (84.0) 0.48
Race and ethnicity (no.)
Asian 26 5 <0.02
Black 20 21
Hispanic 39 16
White 590 290
Other 21 17
Region (no.)
Northeast 104 59 0.31
South 264 147
Midwest 175 75
West 153 68
Affluence status 0.43 ± 0.15 0.39 ± 0.14 <0.01
ASCVD risk factors
Diabetes mellitus (no., %) 35 (5.0) 53 (15.2) <0.01
Hypertension (no., %) 244 (35.1) 210 (60.2) <0.01
Hypercholesterolemia (no., %) 234 (33.6) 201 (57.6) <0.01
Medications (no., %)
Diabetes mellitus 28 (4.0) 46 (13.2) <0.01
Hypertension 99 (14.2) 167 (47.9) <0.01
Hypercholesterolemia 32 (4.6) 101 (28.9) <0.01
Smoking status (no., %)
Current 49 (7.0) 38 (10.9) <0.01
Quit ≤ 1 year 16 (2.3) 32 (9.2)
Quit >1 year 124 (17.8) 106 (30.4)
Never 507 (72.9) 173 (49.5)
Clinical data
Weight (kg) 82.5 ± 24.2 87.9 ± 26.1 <0.01
BMI (kg/m2) 29.3 ± 8.0 31.4 ± 8.7 <0.01
Systolic blood pressure (mmHg)* 116.4 ± 10.5 116.5 ± 14.9 0.98
Diastolic blood pressure (mmHg)* 73.3 ± 7.5 72.6 ± 10.2 0.25
Total cholesterol (mmol/L)* 187.9 ± 22.4 184.6 ± 29.1 <0.05
Blood glucose (mmol/L)* 95.5 ± 16.2 99.9 ± 20.8 <0.01
Diet
Vegetables/day (cups) 1.8 ± 1.3 1.9 ± 1.3 0.79
Fruit/day (cups) 1.4 ± 1.1 1.4 ± 1.1 0.83
Fish (servings/week) 0.8 ± 1.0 0.9 ± 1.0 0.27
Whole grains (servings/day) 1.8 ± 1.3 1.5 ± 1.1 <0.01
Sugar-sweetened beverages (servings/week) 2.8 ± 3.5 2.7 ± 3.4 0.83
Avoid prepackaged foods (no., %) 311 (44.7) 193 (55.3) <0.01
Avoid eating out (no., %) 212 (30.5) 167 (47.9) <0.01
Avoid salt at home (no., %) 308 (44.3) 246 (70.5) <0.01
Exercise
Moderate exercise (min/week) 198.5 ± 211.9 215.5 ± 236.5 0.24
Vigorous exercise (min/week) 76.5 ± 118.1 53.8 ± 107.3 <0.01
Life's Simple 7
Smoking score (no., %) <0.01
Poor 49 (7.0) 38 (10.9)
Intermediate 16 (2.3) 32 (9.2)
Ideal 631 (90.7) 279 (79.9)
Activity score (no., %) 0.08
Poor 14 (2.0) 7 (2.0)
Intermediate 251 (36.1) 146 (41.8)
Ideal 431 (61.9) 196 (56.2)
Diet score (no., %) <0.01
Poor 348 (50.0) 149 (42.7)
Intermediate 303 (43.5) 163 (46.7)
Ideal 45 (6.5) 37 (10.6)
Weight score (no., %) <0.01
Poor 270 (38.8) 172 (49.3)
Intermediate 164 (23.6) 81 (23.2)
Ideal 262 (37.6) 96 (27.5)
Blood glucose score (no., %) <0.01
Poor 16 (2.3) 23 (6.6)
Intermediate 123 (17.7) 87 (24.9)
Ideal 557 (80.0) 239 (68.5)
Cholesterol score (no., %) <0.01
Poor 14 (2.0) 5 (1.4)
Intermediate 207 (29.7) 192 (55.0)
Ideal 475 (68.3) 152 (43.6)
Blood pressure score (no., %) <0.01
Poor 29 (4.2) 25 (7.2)
Intermediate 261 (37.5) 197 (56.5)
Ideal 406 (58.3) 127 (36.4)
LS7 Health Score 7.1 ± 1.5 6.4 ± 1.5 <0.01

*Contains imputed data from Life's Simple 7. Categorical variables are analyzed by Chi-Square test. Continuous variables are analyzed by t-test. Non-parametric variables were analyzed by Wilcoxon rank-sum test. CVD, cardiovascular disease; ASCVD, atherosclerotic cardiovascular disease.