Fig 3. WGS analysis of TE insertion numbers between 5-day young versus 30-day aged RNAi mutant fly strains.
(A-C) Quantification of new TE insertions as compared to the reference genome using the TIDAL program. Categories of total TE insertions broken by the coverage ratios (CR) of CR>2 and CR< = 2. Asterisks mark the library that was downsampled to the equivalent depth of the cognate comparison library. (D-F) Left, 5–95 percentile boxplots of ratios of the 30-day versus 5-day of normalized TE insertions from panels A-C. Right, dot plots display only the TE families with significant changes between the two timepoints in at least one of the mutant strains. (G-I) Boxplots for conducting paired Wilcoxon tests for statistical significance in the gain of unique TE insertions in aging RNAi mutant flies. p-value from Wilcoxon tests, n.s. = not statistically significant.