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. 2022 Mar 3;18(3):e1010042. doi: 10.1371/journal.pgen.1010042

Table 2. Groupings of statistically significantly associated proteins by their biological processes.

Protein Association
Blood group proteins
ABO Risk of hospitalization & need of respiratory support or death due to COVID
KEL Protection against hospitalization
Antigen recognition
CD207 Risk of hospitalization & need of respiratory support or death due to COVID
SFTPD Protection against hospitalization
Adhesion molecules
SELL Protection against hospitalization & need of respiratory support or death due to COVID
SELE Protection against hospitalization & need of respiratory support or death due to COVID
PECAM-1 Protection against hospitalization & need of respiratory support or death due to COVID
sICAM-1 Protection against need of respiratory support or death due to COVID
Transporters
RAB14 Risk of hospitalization & need of respiratory support or death due to COVID
ATP2A3 Protection against hospitalization
Enzymes
GCNT4 Risk of hospitalization & need of respiratory support or death due to COVID
C1GALT1C1 Risk of hospitalization & need of respiratory support or death due to COVID
FAAH2 Risk of hospitalization
LCTL Protection against hospitalization

Note: ABO = ABO system transferase; ATP2A3 = ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3; C1GALT1C1 = C1GALT1 specific chaperone 1; CD207 = langerin; FAAH2 = fatty acid amide hydrolase 2; GCNT4 = glucosaminyl (N-Acetyl) transferase 4; KEL = Kell metallo-endopeptidase (Kell Blood Group); LCTL = lactase-like protein; PECAM1 = platelet endothelial cell adhesion molecule; RAB14 = ras-related protein rab-14; SELE = E-selectin; SELL = L-selectin; SFTPD = surfactant protein D; sICAM1 = soluble intercellular adhesion molecule-1.