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Susceptibility of YFV and DENV to a selection of antiviral agents
| Antiviral agent | EC50 (μg/ml)a for:
|
|
|---|---|---|
| YFV | DENV | |
| Ribavirin | 28 ± 18 | 49 ± 13 |
| EICAR | 0.8 ± 0.6 | 2.4 ± 0.8 |
| Mycophenolic acid | 0.08 ± 0.05 | 0.4 ± 0.3 |
| Tiazofurin | 25 ± 14 | 98 ± 13 |
| Selenazofurin | 3.6 ± 1.5 | 10 ± 5.7 |
Concentration required to reduce the virus-induced cytopathic effect in Vero cells by 50%.
