Table 3. Summary of baseline values (t0) for the swine participating in the pre-clinical trial.
| Parameters | n | Mean | Min. | Q1 | Median | Q3 | Max. | SEM |
|---|---|---|---|---|---|---|---|---|
| Temperature (°C) | 8 | 36.6 | 35.9 | 36.3 | 36.7 | 36.8 | 37 | 0.1 |
| pH | 8 | 7.395 | 7.329 | 7.368 | 7.410 | 7.422 | 7.431 | 0.013 |
| HCO3- (mmHg) | 8 | 32.3 | 29.8 | 30.6 | 32.3 | 33.8 | 34.8 | 0.6 |
| Lactate (mmol/l) | 8 | 1.41 | 0.63 | 1.23 | 1.36 | 1.80 | 1.88 | 0.15 |
| BEecf (mmol/l) | 8 | 7.2 | 5 | 5.5 | 7 | 9 | 10 | 0.7 |
| SaO2 (%) | 8 | 100 | 100 | 100 | 100 | 100 | 100 | 0.0 |
| PaO2 (mmHg) | 8 | 334 | 169 | 278 | 322 | 387.5 | 529 | 37.6 |
| PaCO2 (mmHg) | 8 | 52.9 | 45.1 | 48.3 | 52.6 | 57.6 | 61.4 | 2.0 |
| ETCO2 (mmHg) | 8 | 33.7 | 31 | 32 | 34 | 35.5 | 36 | 0.7 |
| Respiratory rate (breaths/min) | 8 | 37.1 | 20 | 28.5 | 38 | 44 | 56 | 4.1 |
| Heart rate (beats/min) | 8 | 85.4 | 69 | 77.5 | 83.5 | 93.5 | 105 | 4.3 |
| Cardiac output (l/min) | 8 | 5.892 | 3.203 | 4.752 | 6.087 | 7.040 | 8.171 | 0.586 |
After sedation but prior to the induction of deep anesthesia required for connection with Masi mechanical ventilator, cardiorespiratory and physiological parameters were collected for the animals to be used as baseline values. Min.: minimum value, Max.: maximum value, Q1: lower quartile, Q3: upper quartile, SEM: standard error of the mean, pH: potential of hydrogen, HCO3-: bicarbonate ion, BEecf: base excess in the extracellular fluid compartment, SaO2: arterial oxygen saturation, PaO2: arterial oxygen pressure, PaCO2: arterial carbon dioxide pressure, ETCO2: end-tidal carbon dioxide.