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. 2022 Mar 3;17(3):e0264632. doi: 10.1371/journal.pone.0264632

Fig 5. Effects of HWHF on (A & B) gut perfusion, (C) intestinal disaccharidase enzyme activity and, (D) GI motility in high fat fed rats.

Fig 5

Rats were fasted for 36 h, and intestinal perfusion was performed with glucose (54 g/l) with or without HWHF (250 mg/5ml/kg, b.w.). BaSO4 was administered at 1 h following the initial oral dosing. Acarbose (200 mg/5ml/kg, b.w.) and Bisacodyl (1 mg/5ml/kg, b.w.) were used as positive controls for disaccharidase enzyme activity and GI motility, respectively. Values are Mean ± SEM, n = 8. *p<0.05, **p<0.01 and ***p<0.001, compared to control.