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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Free Radic Biol Med. 2021 Nov 12;179:363–374. doi: 10.1016/j.freeradbiomed.2021.11.015

Figure 1: mtHsp70 and mtHsp60 structure and basic function.

Figure 1:

(A) Molecular structure of mtHsp70 with three domains: N-terminal domain (ATP domain), substrate binding domain, and C-terminal domain. (B) Working model of mtHsp70 chaperone system on protein folding. (C) MtHsp60 complexed with cochaperone Hsp10. (D) Working model of mtHsp60 chaperone system on protein folding. Fig.1A and 1C are adapted from prior figures by Kaul et al [128] and Nismeblat et al [43].