Skip to main content
. 2022 Feb 14;18(2):e1010327. doi: 10.1371/journal.ppat.1010327

Fig 1. Influence of S. mansoni infection and age on vaccine-induced anti-poliovirus responses in school children from five schools in a rural region of Cameroon.

Fig 1

(A) Anti-poliovirus IgG levels of a pilot group of school children in the village of Yoro, Bokito in Cameroon in the year 2016 (n = 64). A table indicating the population characteristics is shown below the graph. (B) Anti-poliovirus IgG titre distribution by S. mansoni prevalence and age groups in all children from the five additionally surveyed schools (n = 189). (C) Effect of Schistosomiasis infection, and its treatment with PZQ, on vaccine-induced plasma anti-poliovirus IgG titres in children going from egg-positive to egg-negative for S. mansoni over the 3 years (2016–2018) period (n = 6). (D). Effect of Schistosomiasis infection, and its treatment with PZQ, on vaccine-induced plasma anti-poliovirus IgG titres in children going from egg-negative to egg-positive for S. mansoni over the 3 years (2016–2018) period (n = 2). Data are expressed as mean ± S.D; All data were analysed by Shapiro-Wilk test followed by the two-tailed unpaired Student t test for unequal variances (A, B) and the two-tailed Wilcoxon signed-rank test or paired t test (C,D); ns, p> 0.05; * p< 0.05, ** p< 0.001, *** p< 0.0001; Sm, S. mansoni; PZQ, Praziquantel.