Table 5. Associations between AKI phenotypes and DGF and 1-year eGFR.
Variables | Event Rate in Recipients (n/total) | Univariable [OR (95% CI)] | Multivariable a [OR (95% CI)] |
Association between AKI Phenotypes at anytime during hospitalization and DGF | |||
No AKI | 53/209 (25%) | (ref) | (ref) |
hAKI | 59/184 (32%) | 1.39 (0.87, 2.23) | 1.65 (0.83, 3.27) |
mAKI | 44/159 (28%) | 1.13 (0.67, 1.88) | 1.71 (0.84, 3.50) |
iAKI | 60/117 (51%) | 3.10 (1.87, 5.13) | 4.83 (2.29, 10.22) |
Median (IQR) of 1-year eGFR | Univariable [B coefficient (95% CI)] | Multivariable b [B coefficient (95% CI)] | |
Association between AKI Phenotypes at anytime during hospitalization and 1-year eGFR | |||
No AKI | (ref) | (ref) | |
hAKI | 0.93 (-4.60, 6.47) | 0.88 (-5.56, 7.33) | |
mAKI | 1.01 (-5.04, 7.06) | -1.95 (-8.65, 4.74) | |
iAKI | -4.82 (-10.62, 0.97) | -11.22 (-19.14, -3.30) |
AKI: Acute kidney injury; DGF: Delayed graft function; eGFR: Estimated glomerular filtration rate.
a Multivariable model was adjusted for donor characteristics: KDPI, expanded criteria donor; transport characteristics: Hypothermic machine perfusion and cold ischemia time; and recipient characteristics: Age, black race, male gender, BMI, diabetes as the cause of ESKD, HLA mismatches, PRA, pre-emptive transplant, prior kidney transplant, and duration on dialysis.
b Multivariable model was adjusted for donor characteristics: Age, sex, black race, BMI, HCV status, hypertension, diabetes, stroke as cause of death, donor donation after cardiac death, terminal serum creatinine, expanded criteria donor; transport characteristics: Hypothermic machine perfusion and cold ischemia time; and recipient characteristics: Age, black race, male gender, BMI, diabetes as the cause of ESKD, HLA mismatches, PRA, pre-emptive transplant, prior kidney transplant, and duration on dialysis.