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. 2021 Dec 2;71(3):511–519. doi: 10.2337/db21-0769

Figure 3.

Figure 3

Arterialized plasma concentrations of glucagon (A), epinephrine (B), norepinephrine (C), growth hormone (D), and cortisol (E) during hyperinsulinemic-hypoglycemic clamp studies after 4 weeks of placebo (red squares) or dapagliflozin (Dapa; blue circles) in the crossover study. Data are summarized as medians and 95% CIs. Within-participant differences (placebo minus dapagliflozin) for counterregulatory hormones AUC in response to hypoglycemia for glucagon (F), epinephrine (G), norepinephrine (H), growth hormone (GH; I), and cortisol (J). Black vertical lines signify the median differences for the entire study cohort.