Table 1.
Mycobacterial strains used in this study
| Strain designation | Description | Reference |
|---|---|---|
| Mt103 | clinical isolate of M. tuberculosis lineage 4 | Jackson et al.55 |
| H37Rv | reference laboratory strain of M. tuberculosis | Cole et al.56 |
| H37Rv ΔphoPR | mutant of phoP and phoR genes in H37Rv | Gonzalo-Asensio et al.47 |
| H37Rv ΔphoPR complemented | complemented phoPR genes in H37Rv ΔphoPR strain | Gonzalo-Asensio et al.47 |
| H37Rv ΔRD1 | H37Rv deleted RD1 region | Pym et al.22 |
| BCG Pasteur | current vaccine against TB, attenuated from M. bovis | Brosch et al.21 |
| BCG Danish | current vaccine against TB, attenuated from M. bovis | Brosch et al.21 |
| MTBVAC::hyg (Mt103 ΔfadD26 ΔphoP::hyg) | double marked mutant in phoP with res-Ωhyg-res cassette | Arbues et al.23 |
| MTBVAC | double unmarked mutant of phoP and fadD26 in Mt103 strain | Arbues et al.23 |
| MTBVAC ΔcnpB::km | marked mutant of cnpB gene in MTBVAC | this study |
| MTBVAC ΔdisA::km | marked mutant of disA gene in MTBVAC | this study |