Table 2.
Univariate and multivariate COX regression models for male patients with ACLF.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Variables | HR (95% CI for HR) | p.value | HR (95% CI for HR) | p.value |
| Age (years) |
1.040 (1.010–1.060) |
0.004 | ||
| Cirrhosis | 2.820 (1.490–5.350) |
0.002 | 2.746 (1.229–6.136) |
0.014 |
| BMI (kg/m2) |
0.983 (0.918–1.050) |
0.615 | ||
| Obesity | 0.734 (0.406–1.330) |
0.306 | ||
| ALB (g/L) |
1.000 (0.956–1.050) |
0.915 | ||
| TB (mg/dL) |
1.050 (1.030–1.070) |
0.000 | 1.041 (1.016–1.067) |
0.001 |
| INR | 2.390 (1.570–3.630) |
0.000 | 2.800 (1.798–4.363) |
0.000 |
| CR (mg/dL) |
1.160 (0.642–2.110) |
0.616 | ||
| Na (mmol/L) |
0.912 (0.866–0.960) |
0.000 | ||
| WBC (*109/L) |
0.987 (0.949–1.030) |
0.533 | ||
| PLT (*109/L) |
0.997 (0.993–1.000) |
0.191 | ||
| HGB (g/L) |
0.992 (0.982–1.000) |
0.163 | ||
| MELD score | 1.100 (1.040–1.160) |
0.000 | ||
| Ascites | 3.630 (1.450–9.110) |
0.006 | 4.902 (1.152–20.858) |
0.031 |
| HE | 1.840 (1.060–3.210) |
0.031 | ||
| PMI (cm2/m2) |
0.851 (0.734–0.987) |
0.033 | ||
The multivariate logistic regression model was fited with a stepwise selection method using statistically baseline factors that had been screened in univariate analysis. BMI, body mass index; ALB, albumin; TB, total bilirubin; INR, International normalized ratio; CR, Serum creatinine; Na, Serum sodium; WBC, White blood cell count; PLT, platelet; HGB, hemoglobin; MELD, model for end-stage liver disease; HE, Hepatic encephalopathy; PMI, psoas muscle index.