Table 1. Baseline characteristics and laboratory findings between non-severe and severe groups.
Characteristics | Severity grade | t/χ2 | P-value | |
Non-severe group (n=62) | Severe group (n=23) | |||
aData are presented as mean±SD. P-values were calculated by *chi-square test or #Student's t-test or Mann-Whitney U test. BMI: body mass index; TSF: triceps skinfold thickness; AMC: arm medium circumference; NRS-2002: nutritional risk screening-2002; CRP: C-reactive protein; IL-6: interleukin-6; PaO2/FiO2: arterial partial pressure of oxygen/fraction of inspired oxygen. | ||||
Demographics | ||||
Age (years)a | 59.5±14.5 | 65.1±14.7 | −1.558 | 0.123# |
Male (n [%]) | 26 (41.9) | 14 (60.9) | 2.414 | 0.120* |
Height (cm)a | 163.8±8.5 | 165.3±8.0 | −0.729 | 0.468# |
Weight (kg)a | 61.27±13.3 | 62.80±10.2 | −0.497 | 0.620# |
Underling diseases | ||||
Hypertension (n [%]) | 21 (33.9) | 9 (39.1) | 0.203 | 0.652* |
Coronary heart disease (n [%]) | 7 (11.3) | 5 (21.7) | 1.511 | 0.219* |
Chronic pulmonary obstructive disease (n [%]) | 6 (9.7) | 3 (13.0) | 0.201 | 0.654* |
Nutritional indicatorsa | ||||
BMI (kg/m2) | 22.7±4.1 | 22.9±2.8 | −0.227 | 0.821# |
Serum albumin (g/L) | 39.5±2.9 | 36.2±3.2 | 4.595 | <0.001 # |
Serum prealbumin (g/L) | 287.9±90.0 | 134.4±60.9 | 7.549 | <0.001 # |
TSF (% of normal value) | 102.7±36.3 | 100.6±41.1 | 0.230 | 0.819# |
AMC (% of normal value) | 112.1±14.0 | 103.8±14.7 | 2.351 | 0.024# |
Lymphocyte count (×109/L) | 1.4±0.5 | 1.0±0.5 | 3.150 | 0.002# |
NRS-2002 (point) | 1.4±1.3 | 4.3±1.1 | −9.764 | <0.001 # |
Laboratory indicatorsa | ||||
Leukocytes count (×109/L) | 6.0±2.7 | 7.9±3.7 | −2.187 | 0.036# |
Hemoglobin (g/L) | 118.6±14.4 | 98.4±18.2 |
5.335 |
<0.001 # |
Platelets (×109/L) | 233.7±78.5 | 213.2±109.8 | 0.819 | 0.419# |
Urea (μmol/L) | 4.5±1.2 | 8.2±6.1 | −2.843 | 0.009# |
Creatinine (μmol/L) | 58.7±14.3 | 64.2±29.8 | −0.853 | 0.401# |
CRP (mg/L) | 6.2±10.2 | 44.0±46.3 | −3.743 | 0.001# |
IL-6 (pg/mL) | 15.7±22.5 | 24.9±23.1 | −1.361 | 0.180# |
PaO2/FiO2 | 417.4±79.8 | 211.4±98.1 | 6.142 | <0.001 # |