Figure 1.
Generation of c-Met CAR-T cells.
A: Schematic representations for constructions of 2nd and 3rd-generation c-Met CAR. B: White and GFP photomicrographs (scale bar, 100 μm) of c-Met-28-137-3ζ CAR-T cells revealing GFP-positive clusters. C: Expressions of c-Met CAR were detected by flow cytometry. CAR-T cells are shown in blue and activated T cells in red. Data were the mean±SEM from triplicates. CD8TM: CD8 transmembrane domain; CAR-T: chimeric antigen receptor T-cell; GFP: green fluorescent protein.