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. 2022 Mar 3;13:1137. doi: 10.1038/s41467-022-28722-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a Surface representation of the EndoE-GH18L-Man₅ crystal structure, with annotated domains and loops. b Cartoon representation of the EndoE-GH18L-Man₅ crystal structure. c Surface representation of the GH18 domain of EndoE showing the location of the Man₅ product into the active site. d Electron density map of the Man₅ product shown at 1.0 σ r.m.s.d. e Cartoon representation of the GH18 domain of EndoE showing the location of the Man₅ product into the active site. f Cartoon representation of the GH18 domain of EndoE showing the main residues and secondary structure elements interacting with the Man5 product in the active site. g Superposition of the HM-type N-glycan found in the X-ray crystal structures of EndoE-GH18L (green), EndoBT-3987 (black), and EndoS2 (gray).