Table 3.
AChEI subgroups | Rate (per 105 PYs) | Adjusted HR | 95% CI | 95% CI | P |
---|---|---|---|---|---|
Without AChEI | 362.52 | Reference | |||
With AChEI | 371.04 | 1.198 | 0.765 | 1.774 | 0.167 |
With Donepezil | 367.91 | 1.188 | 0.759 | 1.759 | 0.189 |
With Donepezil, 1–30 days | 363.38 | 1.173 | 0.749 | 1.737 | 0.204 |
With Donepezil, 31–365 days | 369.39 | 1.193 | 0.762 | 1.766 | 0.187 |
With Donepezil, 366–730 days | 365.10 | 1.179 | 0.756 | 1.747 | 0.201 |
With Donepezil, ≥ 731 days | 372.94 | 1.204 | 0.769 | 1.783 | 0.158 |
With Rivastigmine | 369.48 | 1.194 | 0.862 | 1.685 | 0.225 |
With Rivastigmine, 1–30 days | 362.63 | 1.173 | 0.743 | 1.642 | 0.313 |
With Rivastigmine, 31–365 days | 364.59 | 1.178 | 0.751 | 1.659 | 0.286 |
With Rivastigmine, 366–730 days | 373.47 | 1.245 | 1.041 | 1.884 | 0.003 |
With Rivastigmine, ≥ 731 days | 375.29 | 1.297 | 1.043 | 1.889 | 0.001 |
With Galantamine | 367.70 | 1.187 | 0.905 | 1.825 | 0.165 |
With Galantamine, 1–30 days | 363.11 | 1.172 | 0.849 | 1.734 | 0.297 |
With Galantamine, 31–365 days | 365.14 | 1.179 | 0.853 | 1.749 | 0.183 |
With Galantamine, 366–730 days | 366.48 | 1.183 | 0.884 | 1.755 | 0.145 |
With Galantamine, ≥ 731 days | 375.01 | 1.211 | 1.070 | 1.978 | < 0.001 |
PYs person-years, Adjusted HR adjusted hazard ratio: adjusted for the variables listed in Table 3, CI confidence interval.