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. 2022 Mar 3;13:1157. doi: 10.1038/s41467-022-28839-y

Fig. 1. Obesity potentiates B-ALL progression.

Fig. 1

a C57BL/6 mice were maintained on control (Ctrl; 10% fat) and high-fat (HF; 60% fat) diets for 2 months, leading to a significant increase in weight gain in mice fed high-fat diets. Box and Whisker plots display the median, 25th, and 75th percentile. The whiskers extend from the minima to the maxima, respectively. Significance is denoted by **p < 0.01 using a two-sided Student’s t-test (n = 10 mice/group). b Mice fed control and high-fat diets were inoculated intravenously with 105 Bcr-Abl+ Arf−/− murine B-ALL cells (mB-ALL) and survival was monitored. ****P < 0.0001, log-rank test, n = 10 mice/group.