Table 1.
Genes associated with chemoresistance in both human B-ALL cell lines.
| Genes associated with chemoresistance in both human B-ALL cell lines. REH & RCH-AcV (ACM + MTX); p-value cutoff of 0.01 | |
|---|---|
| Upregulated | Downregulated |
| RSPRY1 | CCDC17 |
| RAD17 | LINC00176 |
| SDF2L1 | IK |
| VPS9D1-AS1 | NSMCE2 |
| OXNAD1 | MYO5C |
| STAT6 | ASTN2 |
| MIR7161 | RAN |
| MCMBP | MORF4L2-AS1 |
| LINC00624 | THOP1 |
| ODF2L | CDS2 |
| TSC1 | MOGS |
| LINC00562 | AFF4 |
| PPARGC1B | ‘PIK2IP1 |
| CD3EAP | NAIP |
| SLCO4A1-AS1 | ZFP36L1 |
| ARRDC4 | RAB15 |
| RCN1 | TMEM217 |
| LINC013355 | PEX19 |
| TMEM88 | LIG1 |
| MYD88 | PHLDA3 |
| CNOT8 | GADD45A |
| CHRNA5 | RHEB |
| FMNL2 | TSGA10 |
| HLA-E | |
| CRACR2A | |
| CDNF | |
| LINC01144 | |
| RHNO1 | |
| XYLT1 | |
| EIF5AL1 | |
| PDIA5 | |
| DDN | |
| EFNA3 | |
| SLC25A16 | |
| TLCD1 | |
| GPR137C | |
| ZFP36L2 | |
This table contains genes identified as being associated with chemoresistance in both cell lines using a p-value cutoff of 0.01. Notably, this list did not contain many mediators of cellular aggregation or adhesion, which was a prominent phenotype observed in human B-ALL cells cultured in adipocyte-conditioned media.