Table 1.
Description of studies included in meta-analysis.
| References | Type of study | n | Population considered for meta-analysis | Abnormal GLS-positive | Cut-off of GLS | Mean or median of follow-up | Withdrawal rate |
|---|---|---|---|---|---|---|---|
| Kitano et al. (12) | Retrospective, monocentric, consecutive pts | 325* | asy-AS | 162 (49.8%) | 15.1 | 24 months | 4.41% |
| Thellier et al. (13) | Retrospective, monocentric, consecutive pts | 332 | severe asy-AS, EF ≥ 50% | 192 (57.8%) | 15 | 42 months | 0% |
| Gu et al. (14) | Retrospective, monocentric, consecutive pts | 218 | moderate to severe asy-AS, EF ≥ 50% | 131 (60.1%) | 15 | 33.4 months | 0% |
| Carstensen et al. (15) | Prospective, multicentric | 104 | moderate to severe asy-AS, EF ≥ 50% | 39 (37.5%) | 15 | 2.3 yrs | 0% |
| Nagata et al. (16) | Retrospective, multicentric | 104 | severe asy-AS, EF > 50% | 64 (62.7%) | 17 | 373 days | 1.92% |
| Yingchoncharogen et al. (17) | Prospective, monocentric | 79 | severe asy-AS, EF ≥ 50% | NA | NA | 16 months | 0% |
| Kearney et al. (18) | Prospective, monocentric, consecutive pts | 135* | mild to moderate asy-AS | 54 (40.0%) | 15 | 2.1 yrs | 7.53% |
| Zito et al. (19) | Prospective, monocentric | 52 | severe asy-AS, EF ≥ 50% | NA | NA | 11 months | 16.92% |
| Lancellotti et al. (20) | Prospective, multicentric | 163 | moderate to severe asy-AS, EF ≥ 55% | 79 (48.5%) | 15.9 | 20 months | 0% |
Values are expressed as n (%). Asy-AS, asymptomatic aortic valve stenosis; EF, ejection fraction; GLS, global longitudinal strain; NA, not applicable.
*
The population considered for this meta-analysis is a part of the total population of the original study.