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. 2022 Feb 25;54(2):91–102. doi: 10.1038/s12276-022-00736-w

Fig. 3. Passive release of HMGB1 during cell death.

Fig. 3

HMGB1 is a typical damage-associated molecular pattern (DAMP) that can be passively released during various types of cell death, such as pyroptosis, necrosis, apoptosis, necroptosis, ferroptosis, NETosis, and lysosome-mediated and autophagy-dependent cell death.