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. 2022 Mar 3;12:3544. doi: 10.1038/s41598-022-07420-z

Table 1.

Characteristics of included studies.

Study Design Participants Intervention Outcome
Author, year and country n Age M (SD) Sex Name Description (training content, overall number of sessions, training length per session, delivery mode ) Theory of mind Emotion recognition Social decision-making Perspective taking Others
Age group: 0–18 years, children and adolescents

Bianco et al. (2019)

Italy

Cluster-RCT

Group 1: 27

Group 2: 22

Overall: 7.60 years (3.98 months)

Group 1: 59.25%♀

Group 2: 68.18♀

Group 1: advanced theory of mind

Group 2: control condition

Group 1: two misunderstandings, two sarcasms, two faux-pas und two double-bluff stories in increasing complexity

Group 2: narratives and language exercises referred not to mental, but to physical states

4 sessions, twice a week, 50 min each

Face to face group setting

x Verbal ability, working memory, interference control, shifting, reading comprehension, metacognition

Bianco et al. (2021)

Italy

Cluster-RCT

Group 1: 28

Group 2: 36

Group 3: 27

Overall: 7.59 years (3.97 months)

Group 1: 53.57%♀

Group 2: 50.00%♀

Group 3: 59.26%♀

Group 1: second-order reaction time

Group 2: advanced theory of mind

Group 3: control condition

Group 1: group conversations about narratives & two language exercises

Group 2: two misunderstandings, two sarcasms, two faux-pas und two double-bluff stories in increasing complexity

Group 3: narratives and language exercises referred not to mental, but to physical states

4 sessions, twice a week, 50 min each

Face to face group setting

x Verbal ability, working memory, interference control, shifting, reading comprehension, metacognition

Caputi et al. (2021)

Italy

RCT Overall: 210 Overall: 9.66 years (0.85) Overall:48.00%♀

Group 1: theory of mind training

Group 2: no-theory of mind training

Group 1: group discussion about mentalistic stories which were similar to target strange stories

Group 2: group discussion about physical stories which were similar to target strange stories

5 weekly sessions, 50 min each

Face to face group setting

x Loneliness, verbal abilities, socio-economic status

Carbonero Martin et al. (2013)

Spain

Quasi-experimental

Group 1: 10

Group 2: 10

n.a

Group 1: 50.0% ♀

Group 2: 50.0% ♀

Group 1: mentalist skills

Group 2: control group

Group 1: metacognitive intervention program in which children learn to talk about other people’s mental states, weekly 45 min sessions for 3 months

Group 2: no treatment

Face to face group setting

x Mentalist skills

Guajardo and Watson et al. (2002)

USA

RCT

Group 1: 19

Group 2: 18

Overall: 46.0 (n.a.)a

Group 1: 45.0% ♀

Group 2: 33.3% ♀

Group 1: storytelling training

Group 2: control group

Group 1: stories about maxi and his mother in different everyday situations with false-belief tasks in 12–15 sessions each lasting 15–25 min over a period of 5 weeks

Group 2: no treatment

Face to face group setting

x Language

Hale and Tager-Flusberg (2003)

USA

RCT

Group 1: 20

Group 2: 20

Group 3: 20

Group 1: 47.0 (5.1)a

Group 2: 48.4 (5.9)a

Group 3: 45.6 (6.3)a

Overall: 41.6% ♀

Group 1: false belief

Group 2: sentential complements

Group 3: relative clauses

Group 1: location change story

Group 2: story about action towards a Sesame street character and questions about it

Group 3: two twin characters performed tasks, children had to say which character did what

Two training sessions

Face to face group setting

x Sentential complements, relative clauses

Lecce et al. (2014)

Italy

RCT

Group 1: 33

Group 2: 29

Overall: between 4 and 5 years

Group 1: 51.5% ♀

Group 2: 34.4% ♀

Group 1: theory of mind training

Group 2: control-physical condition

Group 1: ToM training focused on first-order false-belief tasks

Group 2: participants practiced on control-physical stories (stories about events in the physical domains e.g. logical consequences involving humans and animals)

Both training consisted of three 20 min sessions

Face to face individual setting

x Metamemory

Lu et al. (2008)

China

RCT

Group 1: 26

Group 2: 25

Group 1: 43.9 (4.4)a

Group 2: 43.9 (4.9)a

Group 1: 46.1% ♀

Group 2: 56.0% ♀

Group 1: theory of mind training

Group 2: control training

Group 1: storytelling with questions regarding characters of the story

Group 2: storytelling with questions regarding physical features

Four sessions, 10–15 min each

Face to face individual setting

x

Ornaghi et al. (2021)

Italy

RCT Overall: 70 Overall: 3.10 years (5.96 months)

Group 1: 50.00% ♀

Group 2: 50.00% ♀

Group 1: theory of mind training

Group 2: control training

Group 1: storytelling enriched with metal state language and language games

Group 2: storytelling, but free play afterwards

2-month intervention, twice weekly sessions, 20 min each

Face to face group setting

x Metacognition, language, Pragmatic competence

Peskin et al. (2004)

Canada

RCT Overall: 48

Group 1: 4.5 (n.a.)

Group 2: 4.7 (n.a.)

Group 1: 41.66%♀

Group 2: 45.83%♀

Group 1: theory of mind training

Group 2: control training

Group 1: books with test rich in explicit metacognitive terms

Group 2: same books without metacognitive language

4-week intervention

Face to face group setting

x Language, metacognition

Qu et al. (2015)

Singapore

RCT Overall: 71

Group 1: 59.4 (5.4)a

Group 2: 60.6 (5.6)a

Group 3: 60.2(6.1)a

Overall: 47.8%

Group 1: free play

Group 2: sociodramatic play

Group 3: sociodramatic play and theory of mind coaching

Group 1: books and several toys were provided for free play

Group 2: ToM story, participants pretended to be in the story

Group 3: similar to Group 2, with additional support

Four weekly 45 min sessions

Face to face group setting

x Language, executive functions

Rostan et al. (2014)

Spain

RCT Overall: 78

Group 1: 43.8 (1.7)a

Group 2: 42.9 (1.6)a

Group 3: 43.2 (1.9)a

Group 1: 65.0% ♀

Group 2: 58.0% ♀ Group 3: 58.0% ♀

Group 1: SDO training

Group 2: SDN training

Group 3: LAB training

Group 1: sentential complements with deceptive objects (e.g. a candle in the shape of a tomato, children have to talk about what the object is)

Group 2: sentential complements with non-deceptive objects

Group 3: labelling of objects according to characteristics

3 training sessions, each 5–10 min

Face to face group setting

x Vocabulary

Serrat Sellabona et al. (2013)

Spain

RCT Overall: 104, 26 per group Overall: 3.70 (n.a.) n.a

Group 1: discourse training (DIS)

Group 2: labelling training (LAB)

Group 3: sentential complements with non-deceptive objects (SDN)

Group 4: control group (CON)

Group 1: children needed to talk with a puppet about deceptive objects they saw

Group 2: labelling of objects according to characteristics

Group 3: sentential complements with deceptive objects (e.g. a candle in the shape of a tomato, children have to talk about what the object is)

Group 4: deceptive objects were shown but nobody talked

Three training sessions, 10 min each

Face to face group setting

x
Age group: 18–60 years: young and middle aged adults

Alkozei et al. (2018)

USA

RCT

Group 1: 31

Group 2: 31

Group 1: 27.1 (6.7)

Group 2: 26.8 (8.1)

Group 1: 58.6% ♀

Group 2: 50.0% ♀

Group 1: internal awareness training

Group 2: external awareness training

Group 1: program focused on understanding, perceiving, managing and using emotions

Group 2: program focused on learning about external environment (e.g. plants). Both programs consisted of 6 lessons, twice a week for 3 weeks, each session lasting 30–45 min

Online individual setting

x Emotional intelligence

Haut et al. (2019)

USA

RCT

Group 1: 24

Group 2: 21

Group 1: 24.5 (2.9)

Group 2: 24.6 (2.9)

Group 1: 41.7% ♀

Group 2: 53.0% ♀

Group 1: social cognitive training

Group 2: computer game control

Group 1: training focused on training facial emotion recognition, emotional prosody, perspective-taking

Group 2: participants completed common computer games

Both trainings consisted of 15 sessions, each 45 min

Online individual setting

x Empathy, intrinsic motivation

Kemney et al. (2012)

USA

RCT

Group 1: 41

Group 2: 41

Overall: 41.1 (10.4)

Group 1: 100% ♀

Group 2: 100% ♀

Group 1: meditation/emotion training

Group 2: waitlist control group

Group 1: concentration training, mindfulness, promotion of empathy, yoga, emotion recognition

Group 2: waitlist control

Training lasting 8 weeks (42 h)

Face to face group setting

x Mood, stress

Meyer et al. (2016)

USA

RCT

Group 1: 27

Group 2: 27

Group 1: 21.4 (3.5)

Group 2: 21.1 (2.1)

Group 1: 51.8% ♀

Group 2: 51.8% ♀

Group 1: social working memory training

Group 2: cognitive working memory training

Group 1: ranking of friends in working memory training

Group 2: alphabetical ranking in working memory training

Both training consisted of twelve 20 min sessions

Online individual setting

x Working memory

Santiesteban et al. (2012)

UK

RCT

Group 1: 19

Group 2: 17

Group 3: 17

Overall: 26.7(6.6) n.a.

Group 1: imitation training

Group 2: imitation-inhibition training

Group 3: inhibitory control training

Group 1: training focuses on imitation of videos in which either an index or middle finger performed a lifting movement

Group 2: training focuses on not imitating moves from a video, but rather do the opposite (lift the middle finger when the video shows the index finger)

Group 3: stroop-task training

Two training sessions, 40 min each

Face to face individual setting

x x

Valk et al. (2017)

Germany

RCT

Group 1: 80

Group 2: 81

Group 3: 81

Overall: 40.7(9.2) Overall: 59.3% ♀

Group 1 and 2: affect, presence and perspective module

Group 3: only affect module

Group 1 and 2 attended all three modules in a different order. Group 3 only attended the affect training. Trainings lasted 39 weeks, divided in 3 modules, each lasting 12 weeks

Face to face group setting

x Compassion, selective attention
Age group: older than 60 years: older adults

Cavallini et al. (2015)

Italy

RCT

Group 1: 37

Group 2: 26

Group 1: 71.4 (5.1)

Group 2: 71.5 (5.6)

Group 1: 86.5% ♀

Group 2: 85.5% ♀

Group 1: theory of mind training

Group 2: physical-conversation training

Group 1: ToM training focused on tasks and conversations about mental states

Group 2: participants practiced and discussed material about physical occurrences

Both trainings consisted of 4 sessions. No information on training frequency

Face to face group setting

x

Lecce et al. (2015)

Italy

RCT

Group 1: 24

Group 2: 24

Group 3: 24

Group 1: 69.6 (7.3)

Group 2: 65.5 (5.3)

Group 3: 67.7 (5.9)

Group 1: 79.2% ♀

Group 2: 79.2% ♀

Group 3: 70.8% ♀

Group 1: theory of mind training

Group 2: physical conversion training

Group 3: social contact group

Group 1: ToM training focused on tasks and conversations about mental states

Group 2: participants practiced and discussed material about physical occurrences

Group 3: group conversations

Two weekly 2-h training sessions

Face to face group setting

x Metamemory

Lecce et al. (2019)

Italy

Quasi-experiment Group 1: 43 Group 1: 68.3 (6.4) Group 1: 66.6% ♀ Group 1: theory of mind training

Group 1: ToM training focused on tasks and conversations about mental states

Three weekly 2-h training sessions

Face to face group setting

x Updating, set-shifting, verbal knowledge

Rosi et al. (2016)

Italy

RCT

Group 1: 85

Group 2: 83

Group 1: 70.5 (6.9)

Group 2: 68.4 (6.1)

n.a.

Group 1: theory of mind training

Group 2: control group

Group 1: ToM training focused on tasks and conversations about mental states

Group 2: participants practiced and discussed material about physical occurrences

Four 2-h sessions. No information on training frequency

Face to face group setting

x Animation task

RCT randomized controlled trial, ToM theory of mind.

aAge of children was displayed in months.