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. 2022 Feb 8;54(2):115–128. doi: 10.1038/s12276-022-00727-x

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Fig. 4 — a SA-b-gal assay showing increased staining (blue) in α-synuclein-expressing SH-SY5Y cells. b H3K9me3 (red) staining showing elevated heterochromatin DNA foci in α-synuclein-expressing cells (scale bar: 20 μm). The measured H3K9me3 intensity (intensity units; i.u.) was categorized as described (white bar: 0–2000 i.u.; light gray bar: 2001–8000 i.u.; dark gray bar: 8001–15500 i.u.; black bar: >15,501 i.u.). c TEM images showing mitochondria morphologies. Note that normal-appearing mitochondria are indicated by blue arrows, whereas abnormal mitochondria are indicated by red arrows.