Fig. 2.

Landscape of somatic mutation profiles in 500 endometrial cancer samples from TCGA database. AThe waterfall plot shows top 50 mutated genes in each sample. The upper barplot shows the number of mutations in each patient, while the right barplot indicates the number of mutated samples in each gene. B Proportion of tumors in three molecular subtypes of each gene. Green stars showed 4 genes with few mutations in MSI group, red stars showed 6 genes with frequent mutations in MSI group. C Frequently mutated genes in the MSI subgroup. Shown are the mutation numbers of different variant types in six genes