Table 4.
Odds of prevalent moderate and severe vertebral fractures in prediabetes and type 2 diabetes, stratified by sex.
| Men (N = 1709) | Moderate or severe VF (N = 94) | No VF (N = 1613) | Crude OR (95% CI) | Adjusted OR* (95% CI) |
|---|---|---|---|---|
| NGM (n=927) | 49 (5.3%) | 878 (94.7%) | Reference | Reference |
| Prediabetes (n=289) | 20 (6.9%) | 269 (93.1%) | 1.33 (0.78-2.28) | 1.26 (0.72-2.21) |
| T2D (n=493) | 27 (5.5%) | 466 (94.5%) | 1.04 (0.64-1.67) | 1.01 (0.59-1.72) |
| Women (N = 1820) | Moderate or severe VF (N = 59) | No VF (N = 1760) | Crude OR (95% CI) | Adjusted OR* (95% CI) |
| NGM (n=1356) | 42 (3.1%) | 1314 (96.9%) | Reference | Reference |
| Prediabetes (n=241) | 13 (5.4%) | 228 (94.6%) | 1.78 (0.94-3.38) | 1.15 (0.58-2.27) |
| T2D (n=223) | 4 (1.8%) | 219 (98.2%) | 0.57 (0.20-1.61) | 0.32 (0.11-0.96) |
*Logistic regression analysis, adjusted for age, smoking status, bone mineral density, and body mass index.
VF, vertebral fracture; NGM, normal glucose metabolism; T2D, type 2 diabetes; OR, odds ratio; CI, confidence interval.