TABLE 1.

Abscess induction by Zps^a

Polysaccharide	AD50b (μg)
PS A	0.67
PS B	25
CPC	22
C substance	5
S. pneumoniae type 1 CP	31
Group B meningococcal CP	>200
Group B streptococcal type Ia CP	>200

^aAnimals were challenged intraperitoneally with 10-fold dilutions of each polysaccharide mixed 1:1 with sterile cecal-content adjuvant (64). Animals were examined for intra-abdominal abscesses 6 days later, and the AD₅₀ was calculated as described (64). Zps were potent abscess-inducing agents, while polysaccharides that did not have this charge motif had AD₅₀s greater than 200 μg. 

^bThe dose of polysaccharide calculated to yield abscesses in 50% of animals as previously described (64).