TABLE 1.
Death, incident cases, and disability‐adjusted life years (DALYs) for liver cancer in 2019 and percentage change in age‐standardized rates (ASRs) per 100,000 population from 1990 to 2019 by Global Burden of Disease regions
| Characteristics | Death (95% uncertainty interval) | Incidence (95% uncertainty interval) | DALYs (95% uncertainty interval) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Counts | ASR per 100,000 population (95% UI) | Percentage change in ASRs per 100,000 population (95% UI) | Counts | ASR per 100,000 population (95% UI) | Percentage change in ASRs per 100,000 population (95% UI) | Counts | ASR per 100,000 population (95% UI) | Percentage change in ASRs per 100,000 population (95% UI) | |
| Global | 484,577 (444,091 to 525,798) | 5.9 (5.4 to 6.4) | −33.4 (−41.9 to −23.2) | 534,364 (486,550 to 588,639) | 6.5 (5.9 to 7.2) | −27.5 (−37.3 to −15.7) | 12,528,422 (11,400,671 to 13,687,675) | 151.1 (137.5 to 164.8) | −41.5 (−49.8 to −31.5) |
| Sex | |||||||||
| Male | 333,673 (299,581 to 368,334) | 8.7 (7.9 to 9.6) | −32.3 (−42.7 to −19.3) | 376,483 (335,003 to 421,982) | 9.7 (8.7 to 10.8) | −25.7 (−37 to −10.1) | 9,048,723 (8,022,502 to 10,072,046) | 225.3 (200.4 to 250.2) | −40.4 (−50.4 to −27.8) |
| Female | 150,904 (134,123 to 167,013) | 3.5 (3.1 to 3.8) | −35 (−46.3 to −22.4) | 157,881 (140,436 to 176,052) | 3.6 (3.2 to 4) | −30.5 (−42.7 to −17.2) | 3,479,699 (3,108,771 to 3,866,969) | 81.3 (72.7 to 90.3) | −43.3 (−54.2 to −31.2) |
| Regions | |||||||||
| Andean Latin America | 1840 (1510 to 2232) | 3.3 (2.7 to 4) | −36.2 (−49.1 to −20.6) | 1735 (1419 to 2114) | 3.1 (2.5 to 3.8) | −36.4 (−49.6 to −20.1) | 44,340 (35,812 to 54,428) | 77.3 (62.6 to 94.7) | −40.5 (−53.3 to −24.9) |
| Australasia | 2006 (1832 to 2174) | 4.1 (3.8 to 4.5) | 107.8 (91.4 to 124.8) | 2160 (1752 to 2667) | 4.6 (3.7 to 5.7) | 124.1 (82.3 to 176.8) | 43,655 (40,249 to 47,404) | 98.1 (90.3 to 106.4) | 94.8 (77.6 to 112) |
| Caribbean | 1695 (1418 to 2005) | 3.3 (2.8 to 3.9) | −47.7 (−55.7 to −38) | 1628 (1353 to 1938) | 3.2 (2.6 to 3.8) | −46.7 (−55.1 to −36.4) | 41,276 (33,562 to 50,616) | 80.7 (65.6 to 99.2) | −46.8 (−55.7 to −35.5) |
| Central Asia | 6191 (5387 to 7076) | 8.7 (7.6 to 9.9) | 169.6 (129.8 to 214.6) | 6109 (5296 to 7001) | 8.3 (7.2 to 9.4) | 164.3 (124.9 to 209.7) | 172,830 (148,859 to 200,042) | 213.5 (184.9 to 244.5) | 150.2 (111.1 to 196.2) |
| Central Europe | 7202 (6218 to 8327) | 3.4 (2.9 to 3.9) | −39.9 (−48.2 to −30.6) | 6906 (5994 to 7986) | 3.3 (2.9 to 3.8) | −37.4 (−45.7 to −27.8) | 156,614 (133,681 to 182,107) | 79.1 (67.7 to 92.3) | −39.9 (−48.7 to −30.1) |
| Central Latin America | 8416 (7357 to 9750) | 3.6 (3.2 to 4.2) | −2.4 (−14.5 to 12.1) | 7987 (6880 to 9272) | 3.4 (3 to 4) | −1.9 (−14 to 13.4) | 197,475 (171,637 to 231,238) | 82.8 (72.1 to 97) | −7.2 (−19.2 to 7.7) |
| Central Sub‐Saharan Africa | 1394 (1108 to 1753) | 2.5 (2 to 3.1) | −13.3 (−31.8 to 11.5) | 1364 (1080 to 1715) | 2.3 (1.8 to 2.9) | −12.6 (−32.3 to 15.1) | 51,448 (38,555 to 67,260) | 65.3 (51.7 to 82.1) | −15.5 (−36 to 12.1) |
| East Asia | 193,864 (163,848 to 228,758) | 9.4 (8 to 11) | −63.2 (−70.9 to −53) | 217,171 (181,403 to 257,464) | 10.4 (8.8 to 12.3) | −58.7 (−67.7 to −47.3) | 5,491,479 (4,590,535 to 6,534,290) | 263.4 (221.3 to 312.2) | −65.1 (−72.8 to −55) |
| Eastern Europe | 9676 (8506 to 11,122) | 2.9 (2.5 to 3.3) | 85 (64.9 to 108.3) | 9407 (8199 to 10,735) | 2.8 (2.5 to 3.2) | 87.1 (66 to 110) | 234,701 (205,032 to 273,291) | 74.9 (65.3 to 86.6) | 72 (51.5 to 95.4) |
| Eastern Sub‐Saharan Africa | 5677 (4683 to 6919) | 3.4 (2.9 to 4.2) | 8.4 (−10.7 to 32.4) | 5439 (4462 to 6714) | 3.1 (2.6 to 3.8) | 6.6 (−13.2 to 30.7) | 187,944 (149,325 to 232,670) | 85.5 (70.2 to 105.1) | 3 (−20.1 to 30.4) |
| High‐income Asia Pacific | 49,685 (43,778 to 53,504) | 10.8 (9.8 to 11.5) | −7.2 (−14.4 to −0.9) | 67,946 (58,134 to 77,642) | 15.6 (13.5 to 17.7) | 13 (−1.7 to 28.2) | 92,0379 (842,591 to 983,716) | 238.6 (220.6 to 255.5) | −19.3 (−25.4 to −13.2) |
| High‐income North America | 26,479 (23,637 to 28,913) | 4.3 (3.8 to 4.7) | 111.4 (89.3 to 130.2) | 31,008 (25,713 to 36,961) | 5.2 (4.3 to 6.2) | 134.8 (94.1 to 179.3) | 608,194 (543,851 to 664,431) | 105.5 (94.5 to 115.2) | 107 (84.9 to 126.2) |
| North Africa and Middle East | 26,432 (21,211 to 32,611) | 6.2 (5.1 to 7.6) | −3 (−24.7 to 29.5) | 27,546 (22,113 to 33,841) | 6.3 (5.1 to 7.7) | 3.5 (−19.3 to 37.7) | 731,622 (578,678 to 923,575) | 153.3 (121.9 to 189.8) | −4.8 (−27.1 to 27.8) |
| Oceania | 233 (195 to 277) | 3.5 (2.9 to 4.1) | −10.1 (−27.2 to 10.6) | 234 (195 to 278) | 3.3 (2.8 to 3.9) | −10.3 (−27.3 to 10.3) | 7093 (5872 to 8495) | 85.4 (71.3 to 101.6) | −13.1 (−29.3 to 7) |
| South Asia | 38,650 (33,517 to 44,561) | 2.8 (2.4 to 3.2) | −0.5 (−17.2 to 19.7) | 37,733 (32,783 to 43,281) | 2.7 (2.3 to 3.1) | 0.1 (−17.5 to 20.1) | 1,085,515 (943,943 to 1,244,802) | 71.3 (62 to 81.8) | −2.3 (−17.8 to 15.7) |
| Southeast Asia | 42,862 (35,326 to 51,520) | 7.3 (6.1 to 8.8) | 8.3 (−13 to 33.8) | 42,800 (35,218 to 52,129) | 7.1 (5.9 to 8.6) | 10 (−11.2 to 37.7) | 1,149,098 (943,489 to 1,384,243) | 177.5 (146.6 to 213.5) | −1.5 (−20.9 to 21.4) |
| Southern Latin America | 2027 (1897 to 2152) | 2.4 (2.3 to 2.6) | 46.1 (32 to 64.5) | 1939 (1524 to 2424) | 2.3 (1.8 to 2.9) | 49.4 (16.5 to 90.4) | 43,534 (40,967 to 46,273) | 53.6 (50.4 to 57) | 37 (23.3 to 54.3) |
| Southern Sub‐Saharan Africa | 4040 (3618 to 4540) | 7.1 (6.3 to 7.9) | 4.7 (−39.9 to 58.4) | 4016 (3581 to 4521) | 6.8 (6.1 to 7.6) | 4.7 (−40 to 58.8) | 122,195 (108,238 to 137,902) | 188.8 (168.3 to 213) | 3.9 (−40.7 to 57) |
| Tropical Latin America | 5939 (5543 to 6239) | 2.5 (2.3 to 2.6) | 19.1 (12.3 to 26.4) | 5667 (5335 to 5956) | 2.4 (2.2 to 2.5) | 19.7 (13.3 to 27.3) | 142,719 (135,353 to 150,317) | 58.6 (55.4 to 61.7) | 12.4 (6.1 to 19.3) |
| Western Europe | 40,296 (37,224 to 42,876) | 4.4 (4.1 to 4.7) | 28.5 (21.4 to 36.3) | 45,859 (39,837 to 52,739) | 5.3 (4.6 to 6.1) | 49.5 (29.8 to 72.9) | 787,717 (738,440 to 836,208) | 98.5 (93 to 104.5) | 22 (15.2 to 29.9) |
| Western Sub‐Saharan Africa | 9972 (8360 to 11,564) | 5.3 (4.5 to 6) | −8.9 (−26.3 to 11.3) | 9709 (8164 to 11,417) | 4.9 (4.2 to 5.7) | −9.5 (−27.6 to 10.5) | 308,593 (252,949 to 365,495) | 130.8 (109.4 to 152.3) | −13.6 (−31 to 5.3) |