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. 2022 Feb 18;10:793425. doi: 10.3389/fcell.2022.793425

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Copyright © 2022 Dai and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Development of risk signature in the training cohort. (A) Univariate cox regression analysis of OS for each histone acetylation-related regulator, and 8 genes were identified with p < 0.1. (B) Cross-validation for tuning the parameter selection in the LASSO regression. (C) LASSO regression and the coefficients of the 8 OS-related genes. (D) PPI network showing the interactions between the OS-related genes.