Table 2.
Comparison of variables between the mWMH and sWMH groups.
| Variables | mWMH (n = 160) | sWMH (n = 142) | F/Z | P |
|---|---|---|---|---|
| Age (years)b | 62.00 (17.00) | 68.00 (14.50) | 5.433 | 0.000*** |
| BMI (kg/m2)a | 23.94 ± 2.90 | 23.04 ± 3.30 | 3.334 | 0.013* |
| Erythrocyte (× 1012/L)b | 4.23 (0.76) | 4.21 (0.73) | 1.047 | 0.295 |
| Hb (g/L)a | 132.45 ± 16.01 | 128.20 ± 18.34 | 2.340 | 0.033* |
| Platelets (× 109/L)b | 215.00 (82.25) | 219.00 (75.25) | 0.292 | 0.770 |
| Lymphocytes(× 109/L)b | 1.69 (0.80) | 1.57 (0.74) | 1.186 | 0.235 |
| hs-CRP (mg/L)b | 1.83 (3.72) | 2.75 (7.14) | 2.263 | 0.024* |
| Hcy (μmol/L)b | 13.85 (6.24) | 15.22 (6.03) | 2.409 | 0.016* |
| RBP (mg/L)b | 37.80 (13.43) | 36.20 (13.95) | 1.502 | 0.133 |
| Cr (μmol/L)b | 65.00 (23.75) | 69.00 (27.00) | 1.247 | 0.212 |
| UN (mmol/L) b | 5.31 (2.13) | 5.20 (1.92) | 0.892 | 0.372 |
| β2-M (mg/L)b | 2.10 (0.74) | 2.40 (0.93) | 3.655 | 0.000*** |
| ALP (U/L)b | 68.50 (26.00) | 71.50 (21.75) | 0.982 | 0.326 |
| TG (mmol/L)b | 1.38 (0.89) | 1.27 (0.84) | 1.710 | 0.087 |
| HDL-C (mmol/L)b | 1.04 (0.35) | 0.99 (0.41) | 0.953 | 0.340 |
| LDL-C (mmol/L)b | 2.35 (1.41) | 2.28 (1.14) | 1.250 | 0.211 |
| VLDL-C (mmol/L)b | 0.40 (0.26) | 0.35 (0.22) | 1.430 | 0.153 |
| IMA (U/mL)a | 77.16 ± 4.14 | 77.78 ± 4.13 | 0.035 | 0.195 |
| PA (mg/L)a | 266.33 ± 62.06 | 244.54 ± 66.41 | 2.363 | 0.003** |
| MMSEb | 27.00 (5.00) | 24.00 (10.00) | 5.151 | 0.000*** |
| CDTb | 4.00 (1.00) | 3.00 (2.00) | 4.681 | 0.000*** |
| BNTb | 22.00 (4.00) | 19.00 (9.25) | 6.111 | 0.000*** |
| HVLT-Rb | 18.00 (6.00) | 14.00 (8.00) | 5.478 | 0.000*** |
| MBIb | 90.00 (45.00) | 67.50 (46.25) | 3.950 | 0.000*** |
*P < 0.05,**P < 0.01,***P < 0.001. aShown as Mean ± standard deviation. bShown as median (IQR). Abbreviations: ALP, alkaline phosphatase; BNT, Boston Naming Test; β2-M, β2 microglobulin; CDT, Clock Drawing Test; Cr, creatinine; Hb, hemoglobin; Hcy, homocysteine; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; HVLT-R, Hopkins Verbal Language Learning Lest-Revised; IMA, ischemia modified albumin; LDL-C, low-density lipoprotein cholesterol; MBI, modified Barthel index; MMSE, Mini Mental State Examination; mWMH, mild white matter hyperintensities; PA, prealbumin; RBP, retinol binding protein; sWMH, severe white matter hyperintensities; TG, triglycerides; TMT-A, Trail Making Test; UN, urea nitrogen; VLDL-C, very low-density lipoprotein cholesterol.