Table 3.
Genotypic and allelic distribution and association of the polymorphism of the methylenetetrahydrofolate reductase (MTHFR) C677T gene with ischaemic stroke.
| MTHFR C677T | Control group n =168 | Patient group n = 198 | P-value | OR | 95% CI | P-value |
|---|---|---|---|---|---|---|
| Genotype | P = 0.031 | |||||
| CC | 101 (60.12%) | 94 (47.47%) | 1 | |||
| CT | 62 (36.90%) | 72 (36.36%) | 1.716 | 0.998, 2.918 | P = 0.024 | |
| TT | 5 (2.98%) | 32 (16.16%) | 3.563 | 1.412, 4.350 | P < 0.001 | |
| Allele | ||||||
| C | 264 | 260 | P = 0.012 | P = 0.012 | ||
| T | 72 | 136 | 2.136 | 1.724, 2.871 | ||
OR, odds ratio; CI, confidence interval.