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. 2022 Jan 22;9(7):2103485. doi: 10.1002/advs.202103485

Figure 8.

Figure 8

The disassembly mechanism of G‐quadruplex structures by i) glucose substitution of existing boronate ester bonds, breaking the connection between G‐quartets, ii) breaking hydrogen and iminoboronate bonds in G‐quartets through gluconic acid generation in the first cascade reaction, and iii) H2O2 oxidation of boronate ester bonds to phenol.[ 28 , 31 ]