Figure 2.

Illustration of workflow in this study. Between June 2019 and June 2021, this study included primary cohort 3,816 consecutive patients with NSCLC who visited West China Hospital (Sichuan, China) for model development and validation. Additionally, we built a subset (EGFR cohort and PD-L1 cohort) for patients who underwent staining based on histological specimens and molecular test (EGFR, PD-L1), aiming to evaluate the performance of our models on predicting events gene mutation status and gene subtype. Cohort EGFR and PD-L1 was used to evaluate model performance in joint immunity prediction.