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. 2022 Feb 18;16:747215. doi: 10.3389/fnhum.2022.747215

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Copyright © 2022 Pasquini, Di Napoli, Rossi-Espagnet, Visconti, Napolitano, Romano, Bozzao, Peck and Holodny.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A 47-year-old woman with chronic (>six months) left ischemia and naming aphasia. (A) tb-fMRI [naming task; p < 0.05; FEW corrected (T = 4.70); without restriction of cluster size (k = 0)] shows high BOLD bilateral activation, especially in the right frontal area; (B) after anomia treatment, naming tb-fMRI [p < 0.05; FEW corrected (T = 4.70); without restriction of cluster size (k = 0)] shows reduced BOLD activation with particular reference to the right hemisphere BOLD signal. These results were interpreted as neural priming with better neural efficient associated with less effort. Courtesy of Nardo et al. (2017) Brain 2017; funded by Wellcome Trust Senior Research Fellowship in Clinical Science (106161/Z/14/Z); MRC Clinical Scientist Fellowship (G0701888).