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. 2022 Feb 18;16:747215. doi: 10.3389/fnhum.2022.747215

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Copyright © 2022 Pasquini, Di Napoli, Rossi-Espagnet, Visconti, Napolitano, Romano, Bozzao, Peck and Holodny.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Example of atypical lateralization in a patient with drug-resistant epilepsy from perinatal ischemic lesion, displayed on a verb generation task [p < 0.05; FEW corrected; without restriction of cluster size (k = 0)]. (A) T2-weighted images on the axial planes show a large area of cystic encephalomalacia in the outcome of left frontal-insular-parietal perinatal infarction. The fMRI exam performed with a verb generation task (B) documents the activation of right frontal areas, including the inferior frontal gyrus [arrow in panel (B)]. The story listening task (C) documents the activation of right a temporal area [arrow in panel (C)], representing Wernicke’s area homologous.