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. 2000 Oct;13(4):615–650. doi: 10.1128/cmr.13.4.615-650.2000

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Copyright © 2000, American Society for Microbiology

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FIG. 1 — Origin and fate of phagocytes: a brief overview of the differentiation pathways of phagocytes and their fate. Details are given in the text. Abbreviations: CFU-GEMM/GM/G/M: colony-forming unit granulocyte-erythrocyte-monocyte-megakaryocyte/granulocyte-monocyte/granulocyte/monocyte; AMP/MP alveolar macrophage/macrophage; Pox+/− gr, peroxidase-positive/negative granules; hl, half-life; BMR, bone marrow reserve; cGp/mGp, circulating/marginated granulocyte pool; , decrease; solid arrowheads, factors involved in cell maturation (for example, CSF and cytokines); open arrowheads, influence of the microenvironment in cell maturation (cell receptors and matrix proteins); dashed curved lines, self-renewal potential of phagocyte precursors.

Inline graphic — Origin and fate of phagocytes: a brief overview of the differentiation pathways of phagocytes and their fate. Details are given in the text. Abbreviations: CFU-GEMM/GM/G/M: colony-forming unit granulocyte-erythrocyte-monocyte-megakaryocyte/granulocyte-monocyte/granulocyte/monocyte; AMP/MP alveolar macrophage/macrophage; Pox+/− gr, peroxidase-positive/negative granules; hl, half-life; BMR, bone marrow reserve; cGp/mGp, circulating/marginated granulocyte pool; , decrease; solid arrowheads, factors involved in cell maturation (for example, CSF and cytokines); open arrowheads, influence of the microenvironment in cell maturation (cell receptors and matrix proteins); dashed curved lines, self-renewal potential of phagocyte precursors.