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. 2022 Mar 3;140(4):354–361. doi: 10.1001/jamaophthalmol.2022.0055

Table 2. Univariable and Multivariable Logistic Regression for the Association Between Cost-Related Barriers to Medication Adherence by Race and Ethnicity.

Variable Non-Hispanic White (n = 2875) Non-Hispanic African American (n = 481) Non-Hispanic Asian (n = 119) Hispanic (n = 351)
OR (95% CI) P valuea OR (95% CI) P valuea OR (95% CI) P valuea
Univariable logistic regression
Could not afford medication 1 [Reference] 3.21 (2.44-4.19) <.001 1.69 (0.89-2.94) .09 2.83 (2.06-3.86) <.001
Skipped medication to save money 1 [Reference] 2.55 (1.80-3.58) <.001 1.17 (0.45-2.49) .72 1.47 (0.90-2.30) .14
Took less medication to save money 1 [Reference] 2.10 (1.49-2.93) <.001 1.34 (0.59-2.63) .44 1.30 (0.81-2.01) .34
Delayed filling medication 1 [Reference] 1.97 (1.45-2.65) <.001 1.61 (0.85-2.80) .12 1.54 (1.05-2.21) .03
Asked for lower-cost medication 1 [Reference] 0.82 (0.63-1.06) .26 0.89 (0.54-1.42) .65 1.11 (0.84-1.46) .58
Bought medications from another country 1 [Reference] 0.10 (0.02-0.32) .002 2.00 (0.92-3.84) .07 1.17 (0.66-1.94) .57
Used alternative medication to save money 1 [Reference] 1.59 (1.06-2.33) .03 1.11 (0.43-2.37) .80 1.75 (1.11-2.64) .02
Multivariable logistic regressionb
Could not afford medication 1 [Reference] 1.82 (1.34-2.44) <.001 1.67 (0.85-3.03) .14 1.77 (1.25-2.49) .002
Skipped medication to save money 1 [Reference] 1.27 (0.87-1.85) .36 1.02 (0.38-2.29) .96 0.77 (0.46-1.24) .47
Took less medication to save money 1 [Reference] 1.16 (0.80-1.67) .62 1.21 (0.52-2.49) .78 0.75 (0.45-1.20) .44
Delayed filling medication 1 [Reference] 1.14 (0.82-1.58) .47 1.31 (0.67-2.38) .47 0.91 (0.61-1.35) .69
Asked for lower-cost medication 1 [Reference] 0.78 (0.58-1.02) .13 0.89 (0.53-1.44) .70 1.20 (0.89-1.60) .33
Bought medications from another country 1 [Reference] 0.12 (0.02-0.40) .04 2.27 (1.03-4.45) .17c 1.48 (0.80-2.58) .55
Used alternative medication to save money 1 [Reference] 0.97 (0.63-1.46) .99 0.88 (0.33-1.94) .97 1.15 (0.71-1.80) .82

Abbreviation: OR, odds ratio.

a

P values were generated using the Holm-Bonferroni adjustment for multiple comparisons, while 95% CIs are unadjusted for Holm-Bonferroni.

b

Adjusted for age, gender, insurance status, education, and income.

c

P value without Holm-Bonferroni adjustment = .03.