TABLE 1.
Percent sequence identities among ETD and other ETs.
| Proteins | ETD_Sa | ETA_Sa | ETB_Sa | ETE_Sa | ExhC_Ss | TLP_Sd | TLP_Sf | TLP_Sp | ETB_Sh | ExhC_Sc |
|---|---|---|---|---|---|---|---|---|---|---|
| ETD_Sa | — | 50% | 62.62% | 57.09% | 45.16% | 69.40% | 67.50% | 65.36% | 66.60% | 43.48% |
| ETA_Sa | 50% | — | 44.00% | 43.35% | 44.85% | 42.98% | 47.41% | 43.32% | 47.14% | 38.61% |
| ETB_Sa | 62.62% | 44.00% | — | 55.36% | 37.19% | 60.63% | 64.64% | 55.91% | 59.48% | 39.44% |
| ETE_Sa | 57.09% | 43.35% | 55.36% | — | 40.16% | 56.38% | 63.27% | 58.91% | 59.63% | 43.03% |
| ExhC_Ss | 45.16% | 44.85% | 37.19% | 40.16% | — | 40.41 | 46.88% | 39.63% | 44.24% | 38.57% |
| TLP_Sd | 69.40% | 42.98% | 60.63% | 56.38% | 40.41% | — | 64.29% | 64.29% | 66.92% | 39.29% |
| TLP_Sf | 67.50% | 47.41% | 64.64% | 63.27% | 46.88% | 64.29% | — | 60.07% | 67.16% | 41.04% |
| TLP_Sp | 65.36% | 43.32% | 55.91% | 58.91% | 39.63% | 64.29% | 60.07% | — | 70.36% | 39.13% |
| ETB_Sh | 66.60% | 47.14% | 59.48% | 59.63% | 44.24% | 66.92% | 67.16% | 70.36% | — | 41.42% |
| ExhC_Sc | 43.48% | 38.61% | 39.44% | 43.03% | 38.57% | 39.29% | 41.04% | 39.13% | 41.42% | — |
ETD_Sa, exfoliative toxin D, Staphylococcus aureus, Gene Bank ID: AHC54578.1; ETA_Sa, epidermolytic toxin A from S. aureus, PDB ID: 1AJGJ; ETB_Sa, crystal structure of exfoliative toxin B, PDB ID: 1DT2; ETE_Sa, exfoliative toxin E from S. aureus, Gene Bank ID: WP_054190843.1, PDB ID: 5C2Z; ExhC_Ss, exfoliative toxin ExhC from S. sciuri, Gene Bank ID: AEF13380.1; TLP_Sd, trypsin-like peptidase domain–containing protein from S. delphini, Gene Bank ID: WP_096546202.1; TLP_Sf, trypsin-like peptidase domain–containing protein from S. felis, Gene Bank ID: WP_103209705.1; TLP_Sp, trypsin-like peptidase domain–containing protein from S. pseudintermedius, Gene Bank ID: WP_100002848.1; ETB_Sh, exfoliative toxin B from S. hyicus, Gene Bank ID: BAA99411.1; ExhB_Sc: exfoliative toxin ExhB from S. chromogenes, Gene Bank ID: AAV98626.1.