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. 2022 Feb 18;12:826655. doi: 10.3389/fonc.2022.826655

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Copyright © 2022 VanderVere-Carozza, Gavande, Jalal, Pollok, Ekinci, Heyza, Patrick, Masters, Turchi and Pawelczak

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meyer retrospective analysis of overall survival as a function of replication protein A (RPA) gene expression in non-small cell lung cancer (NSCLC). Blue numbering indicates patients with low RPA expression, red numbering indicates patients with high RPA expression. Analysis represents a 500-patient cohort from the caARRAY, with optimized cutoff. (A) Former and current smokers. HR = 1.63 (1.17–2.28) log-rank: p = 0.0035. (B) Former and current smokers who received chemotherapy. HR = 1.69 (1–2.86) log-rank: p = 0.049. (C) Never smokers.