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4-AAQB treatment inhibits cell cycle progression and viability. (A) Structure of 4-AAQB. (B) MiaPaCa-2 and (C) MiaPaCa-2GEMR cell viability was determined using MTT assays. Cell cycle analysis of (D) MiaPaCa-2 and (E) MiaPaCa-2GEMR cells was carried out using flow cytometry. *P<0.05, **P<0.01, and ***P<0.001 vs. the untreated control cells. 4-AAQB, 4-Acetylantroquinonol B; GEMR, gemcitabine-resistant.
