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. 2022 Feb 18;23(4):128. doi: 10.3892/ol.2022.13248

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 10. — 4-AAQB inhibits the invasiveness of MiaPaCa-2 and MiaPaCa-2^GEMR cells. Cells were treated with 4-AAQB (2 and 5 µM) for 48 h. (A) MiaPaCa-2 cell invasion was assessed using a Transwell assay. Representative images of the invasive cells are shown. (B) The number of invasive MiaPaCa-2 cells was calculated. (C) MiaPaCa-2^GEMR cell invasion was assessed using a Transwell assay. Representative images of the invasive cells are shown. (D) The number of invasive MiaPaCa-2^GEMR cells was calculated. *P<0.05 and **P<0.01 vs. the untreated control cells; ^#P<0.05, ^##P<0.01, and ^###P<0.001 vs. the gemcitabine treated cells; ^@P<0.05 and ^@@P<0.01 vs. the 4-AAQB treated cells. 4-AAQB, 4-Acetylantroquinonol B; GEMR, gemcitabine-resistant.