Figure 4.
4-AAQB treatment downregulates the levels of autophagy-associated proteins in MiaPaCa-2 and MiaPaCa-2GEMR cells. (A) The expression of Atg5, Beclin-1 and LC3 II was analyzed using western blotting. (B-D) Semi-quantification of Atg5, Beclin-1 and LC3 II protein levels. *P<0.05 vs. the untreated control cells. 4-AAQB, 4-Acetylantroquinonol B; GEMR, gemcitabine-resistant; Atg5, autophagy-related 5.