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. 2022 Feb 18;23(4):128. doi: 10.3892/ol.2022.13248

Figure 8.

Figure 8.

4-AAQB enhances chemosensitivity to gemcitabine. (A and B) MiaPaCa-2 and MiaPaCa-2GEMR cells were treated with the indicated concentrations of 4-AAQB and GEM for 48 h. The viability of (A) MiaPaCa-2 and (B) MiaPaCa-2GEMR cells was determined using MTT assays. (C and D) The cells were pretreated with 4-AAQB (2 and 5 µM) for 48 h and then incubated with GEM for another 48 h. The viability of (C) MiaPaCa-2 and (D) MiaPaCa-2GEMR cells was determined using MTT assays. *P<0.05 **P<0.01, and ***P<0.001 vs. the untreated control cells; #P<0.05 and ##P<0.01 vs. the gemcitabine treated cells; @P<0.05 vs. the 4-AAQB treated cells. 4-AAQB, 4-Acetylantroquinonol B; GEMR, gemcitabine-resistant.