| Study | Reason for exclusion |
|---|---|
| Al‐Samkari 2020 | Ineligible study design. Retrospective cohort study without a parallel comparator group of intervention |
| Artifoni 2020 | Ineligible study design. Retrospective cohort study without a comparator group (single‐arm study) |
| Ayerbe 2020 | Ineligible study design. Retrospective cohort study |
| ChiCTR2000034796 | Ineligible study design. Retrospective cohort study comparing people hospitalised with COVID‐19 receiving LMWH versus those not receiving LMWH |
| CTRI/2021/01/030373 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| D'Ardes 2021 | Ineligible study design. Retrospective cohort study without a prospective parallel comparator group of intervention |
| DCTC 2021 | Ineligible study design. Prospective cohort study without a comparator group (single‐arm study) |
| Di Castelnuovo 2021 | Ineligible study design. Retrospective cohort study comparing people hospitalised with COVID‐19 receiving anticoagulation versus those not receiving anticoagulation |
| EUCTR2020‐001748‐24‐SE | Ineligible participants. The RCT did not assess the effects of any anticoagulant |
| EudraCT2020‐001823‐15 | Ineligible study design. Prospective cohort study without a comparator group (single‐arm study) |
| Falcone 2020 | Ineligible study design. Prospective cohort study without a comparator group (single‐arm study) |
| Frohlich 2021 | Ineligible study design. Retrospective cohort study without a comparator group (single‐arm study) |
| Helms 2020 | Ineligible study design. Prospective cohort study without an intervention purpose |
| Helms 2021 | Ineligible study design. Prospective cohort study comparing prophylactic and therapeutic anticoagulant |
| Ho 2021 | Ineligible study design. Retrospective cohort study comparing people hospitalised with COVID‐19 receiving anticoagulants versus people not receiving anticoagulants in USA |
| Huang 2020 | Ineligible study design. Case report |
| Ionescu 2020 | Ineligible study design. Prospective cohort study comparing people hospitalised with COVID‐19 receiving anticoagulants (higher dose) versus anticoagulants (lower dose) in USA |
| Jiménez‐Soto 2021 | Ineligible study design. Prospective cohort study comparing people hospitalised with COVID‐19 receiving anticoagulants (higher dose) versus anticoagulants (lower dose) in Mexico |
| Jonmarker 2020 | Ineligible study design. Prospective cohort study comparing people hospitalised with COVID‐19 receiving three different doses of anticoagulants in Sweden |
| Khider 2020 | Ineligible study design. Prospective cohort study without a parallel comparator group of intervention |
| Kodama 2020 | Ineligible study design. Retrospective cohort study comparing people hospitalised with COVID‐19 receiving 2 different doses of anticoagulants in USA |
| Kow 2020 | Ineligible study design. Letter to editor |
| Kukin 2020 | Ineligible participant. RCT comparing non‐pharmacological intervention for people without COVID‐19 |
| Liu 2020 | Ineligible study design. Retrospective cohort study |
| Mareev 2020 | Ineligible intervention. RCT comparing anti‐inflammatory pharmacological interventions. There is no comparison with anticoagulants |
| Martinelli 2020 | Ineligible study design. Prospective cohort study comparing people hospitalised with COVID‐19 receiving two different doses of anticoagulants |
| Maurer 2020 | Ineligible intervention. RCT comparing arterial line heparinisation versus no‐heparinisation in people hospitalised with COVID‐19 |
| NCT04354155 | Ineligible study design. Prospective cohort study without a parallel comparator group of intervention |
| NCT04359212 | Ineligible study design. Prospective cohort study without a parallel comparator group of intervention |
| NCT04365309 | Ineligible intervention. RCT of aspirin for COVID‐19. There is no difference between the intervention groups regarding anticoagulants. |
| NCT04368377 | Ineligible study design. Prospective cohort study without a comparator group (single‐arm study) |
| NCT04393805 | Ineligible study design. Retrospective cohort study |
| NCT04427098 | Ineligible study design. Prospective cohort study without a comparator group (single‐arm study) |
| NCT04483830 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04492254 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04504032 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04516941 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04662684 | Ineligible participants. RCT where the participants received the intervention after hospital discharge (non‐hospitalised people with COVID‐19) |
| NCT04673214 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04715295 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04736901 | Ineligible study design. Prospective cohort study comparing five different anticoagulant regimens |
| NCT04757857 | Ineligible participants. RCT of non‐hospitalised people with COVID‐19 |
| NCT04828772 | Ineligible study design. Retrospective cohort study comparing people hospitalised with COVID‐19 receiving anticoagulants versus people not receiving anticoagulants in Japan |
| Paranjpe 2020 | Ineligible study design. Retrospective cohort study |
| Piagnerelli 2020 | Ineligible study design. Letter to editor |
| Poulakou 2021 | Ineligible study design. Retrospective cohort study comparing different doses of anticoagulants in people hospitalised with COVID‐19 |
| Qin 2021 | Ineligible study design. Retrospective cohort study comparing different doses of anticoagulants in people hospitalised with COVID‐19 |
| Rosovsky 2020 | Ineligible study design. Prospective survey about physician practice. There was no participant with COVID‐19. |
| Russo 2020 | Ineligible study design. Retrospective cohort study |
| Secco 2020 | Ineligible study design. Retrospective cohort study comparing different doses of anticoagulants in people hospitalised with COVID‐19 |
| Shi 2020 | Ineligible study design. Retrospective cohort study |
| Sivaloganathan 2020 | Ineligible study design. Case‐control study comparing mortality in people hospitalised with COVID‐19 who previously used anticoagulants and antiplatelet agents versus those who did not |
| Smith 2020 | Ineligible study design. Prospective survey about physician practice. There was no participant with COVID‐19. |
| Stessel 2020 | Ineligible study design. Prospective before‐after cohort study without a parallel comparator group |
| Tacquard 2021 | Ineligible study design. Prospective cohort study comparing different doses of anticoagulants in people hospitalised with COVID‐19 |
| Tamargo 2021 | Ineligible study design. Editorial |
| Tang 2020 | Ineligible study design. Retrospective cohort study |
| Trinh 2020 | Ineligible study design. Retrospective cohort study |
| Zhang 2020 | Ineligible study design. Retrospective cases series. Description of 7 participants without a consistent comparator group |
LMWH: low molecular weight heparin, RCT: randomised controlled trial